Business Type:Trading Company
Product Certification&
Enterprise Certification
Country: China (Mainland)
Business Type:Trading Company
CAS NO.850140-72-6
afatinib
afatinib brief description
cas no.:850140-72-6
mf:c24h25clfn5o3
mw:485.9384032
competitive price with high quality
conforms to bp/usp/ep/fcc
afatinib coa
item |
standard |
results |
appearance |
off-white powder |
off-white powder |
identification |
hplc ,nmr |
complies |
residue on ignition |
≤0.10% |
0.05% |
loss on drying |
≤0.50% |
0.15% |
heavy metal |
≤20ppm |
<20ppm |
purity(hplc) |
≥99.0% |
99.99% |
conclusion |
it complies with enterprise standard |
medical use
afatit has received regulatory approval for use as a treatment for non-small cell lung cancer,although there is emerging evidence to support its use in other cancers such as breast cancer.
in october 2010 a phase iii trial in nsclc patients called lux-lung 5 began with this drug.fall 2010 interim results suggested the drug extended progression-free survival threefold compared to placebo, but did not extend overall survival.in may 2012, the phase iib/iii trial lux-lung 1 came to the same conclusion.
in january 2015 a phase iii trial in people with nsclc suggested the drug extended life expactancy in stage iv nsclc adenocarcinoma with egfr mutation type del 19-positive tumors, compared to cisplatin-based chemotherapy by a year (33 months vs. 21 months).
phase ii results for breast cancer that over-expresses the protein human epidermal growth factor receptor 2 (her2-positive breast cancer) were described as promising by the authors, with 19 of 41 patients achieving benefit from afatinib.[9] double-blind phase iii trials are under way to confirm or refute this finding. her2-negative breast cancers showed limited or no response to the drug.
1.good quality
1) good quality is the basic of our goal;
2) we can offer samples to be tested;
3) 98% of our products have exported to uk, usa, germany, spain, australia, middle east and many other countries.
4) Good feedback of quality from our customers.Many customers return orders.
5) professional stuff to supervise the production process of the factory. take pictures and feed back to the customer in every important link.
We have our own factory, thus we can control the whole process of product in our daily work.
6) all purity≥99%
2.lower price
1) )we are manufacturer and can provide high quality products with factory price.
2) we have been in steroid business for many years,we have many experiences in the price.
3) The offer ,trade terms and payment is negotiable. Everything can be consulted with each other.
3.safe and fast delivery
1) most steroids are in large stock, so the products can be sent out within 24 hours after payment confirmed, tracking number and packing details will be informed asap;
2) we can use special package like snacks, shampoo and others to pack products, it's very hidden and convenient;
3)customs pass rate ≥99%
4) secure and discreet shipment. various transportation methods for your choice,by sea, by air are all available
4.professional loading:
1)we have one team supervise uploading the materials. we will check the container, the packages
2)We are pros,we kown our products very well. We also know the market conditions. We will inform you the latest news of market fluctuation,exchange rate fluctuation and so on
in advance.
5.good service.
1)mixed container, we can mix different items in one container.
2) take pictures and feed back to the customer in every important link.
3) cargoes photo before and after loading into container
4) tell the package update asap, and will try best solve when customer encountered various problems.
5)best service after shipment with e-mail