Keywords

• Alogliptin benzoate
• 850649-62-6
• Small molecule inhibitors

Quick Details

• ProName: Alogliptin benzoate CAS NO.850649-62-6
• CasNo: 850649-62-6
• Molecular Formula: C18H21N5O2.C7H6O2
• Appearance: White powder
• Application: Liralitin intermediate
• DeliveryTime: Within ten working day
• PackAge: 1KG;10KG;100KG
• Port: Shang hai
• ProductionCapacity: 5000 Metric Ton/Day
• Purity: 99%
• Storage: Keep container closed and store in coo...
• Transportation: by sea or by air
• LimitNum: 10 Gram
• Moisture Content: <0.01
• Impurity: 0.001%

Superiority

Incretin is a peptide hormone produced by gastrointestinal tract after meal, which can promote the secretion of insulin by islet β cells

It includes glucagon like peptide-1 (GLP-1) and Glucose dependent insulinotropic peptide (GIP), which are secreted by L cells in ileum and colon and K cells in duodenum, respectively. GLP-1 and GIP, as active hormones, can be released into the blood circulation within a few minutes after ingestion of food, but they will be rapidly degraded and inactivated by serine protease DPP-4.

The level of postprandial incretin in patients with type 2 diabetes mellitus is significantly lower, so preventing the inactivation of incretin to increase its action time will effectively reduce blood glucose.

As a DPP-4 inhibitor, agliptin benzoate can reduce the inactivation of GLP-1 in vivo by selectively inhibiting DPP-4, increase the level of GLP-1 in vivo, and reduce blood glucose. When the blood glucose is reduced to the normal level, it will not continue to play a hypoglycemic role, so it can effectively reduce the risk of hypoglycemia.

In addition, DPP-4 inhibitors can delay gastric emptying, increase satiety, inhibit appetite, and help patients reduce body weight.

Therefore, these drugs can effectively reduce blood glucose, but also reduce the risk of hypoglycemia and increased body weight, overcome the obstacles of patients' treatment, and bring new hope to the treatment of diabetes.

Details

Q1: Can i get some samples

A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q2: How to start orders or make payments 

A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, , Paypal or Escrow.

Q3: How to confirm the Product Quality before placing orders 

A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q4:What's your MOQ 

A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Q5: How about delivery lead time 

A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

Q6:Is it OK to print my logo on package

A:Sure.Please inform and offer your Logo formally before production.