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Country: China (Mainland)
Business Type:Trading Company
CAS NO.1143-38-0
anthralin 1143-38-0
product name: anthralin
cas number: 1143-38-0
specification: 99% min
appearance : white or almost white crystalline powder
anthalin accumulates in mitochondria where it interferes with the supply of energy to the cell, probably by the oxidation of dithranol releasing free radicals. this impedes dna replication and so slows the excessive cell division that occurs in psoriatic plaques. in addition dithranol may act by reducing the elevated levels of cgmp that occurs in psoriasis.
anthralin is a synthetic compound whose precise mechanism of anti-psoriatic action is not yet fully understood. however, numerous studies have demonstrated anti-proliferative and anti-inflammatory effects of anthralin on psoriatic and normal skin. the anti-proliferative effects of anthralin appear to result from both an inhibition of dna synthesis as well as from its strong reducing properties.
recently, anthralin’s effectiveness as an anti-psoriatic agent has also been in part attributed to its abilities to induce lipid peroxidation and reduce levels of endothelial adhesion molecules which are markedly elevated in psoriatic patients. unlike retinoids and puva, anthralin does not inhibit liver microsomal enzyme activity; consequently, the likelihood of adverse drug interactions is greatly reduced when other agents are administered concomitantly with anthralin.
side effects
it temporarily stains the skin a yellowy-brown and permanently stains clothing fabrics. it may cause a local burning sensation and irritation; this may be minimised by careful attention to the details of treatment and only gradually stepping up through the strengths of dithranol formulations. the surrounding skin can be protected using soft white paraffin and the treated area is covered with tube gauze.
Q1: Can i get some samples
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2: How to start orders or make payments
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, , Paypal or Escrow.
Q3: How to confirm the Product Quality before placing orders
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q4:What's your MOQ
A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5: How about delivery lead time
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6:Is it OK to print my logo on package
A:Sure.Please inform and offer your Logo formally before production.