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CAS NO.61-54-1
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Tryptamine is a monoamine alkaloid. It contains an indole ring structure, and is structurally similar to the amino acid tryptophan, from which the name derives. Tryptamine is found in trace amounts in the brains of mammals and is hypothesized to play a role as a neuromodulator or neurotransmitter. Similar to other trace amines, tryptamine binds to human trace amine-associated receptor 1 (TAAR1) as an agonist.
Tryptamine is the common functional group in a set of compounds termed collectively substituted tryptamines. This set includes many biologically active compounds, including neurotransmitters and psychedelic drugs.
Name |
Tryptamine |
Synonyms |
2-(3-Indolyl)ethylamine; 3-(2-Aminoethyl)indole |
Molecular Formula |
C10H12N2 |
Molecular Weight |
160.21 |
CAS Registry Number |
61-54-1 |
EINECS |
200-510-5 |
Melting point |
113-117 ºC |
Boiling point |
137 ºC (0.15 mmHg) |
Flash point |
185 ºC |
Water solubility |
negligible |
Item | Standard | Test Results | |
Identification | A.H-NMR:Comply with the structure | Complies | |
B.LC-MS:Comply with the structure | Complies | ||
C.The IR spectrum of sample should be identical with that of reference standard; | Complies | ||
D.HPLC-ESI-MS | Complies | ||
The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. | |||
Loss on drying | ≤0.5% | 0.11% | |
Heavy metals | ≤10 ppm | <10ppm | |
Sulphated ash | ≤0.2%, determined on 1.0 g. | 0.01% | |
Related substances | Unspecified impurities: for each impurity | ≤0.10% | <0.10% |
Total Impurity | ≤1.0% | 0.18% | |
Purity | ≥99.0% | 99.82% | |
Assay | 99.0%~101.0% (anhydrous substance). | 99.90% |
Application
Tryptamine was used in:1 .multi-layered analysis, used to differentiate and identify biogenic amines 2. in the synthesis of indole ring-terminated thiol, ω-mercaptooctyltryptamide 3.in surface-enhanced Raman spectroscopic investigation of indole ring-terminated self-assembled monolayer on gold electrode
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